Lewin, attending his 205th match as England physio, endured the harm when he jumped up to rejoice Daniel Sturridge's equaliser in Manaus and arrived down on a drinking water bottle, twisting his ankle.
Scans exposed he experienced dislocated and fractured his ankle in what supervisor Roy Hodgson described as a " incredibly unpleasant " incident.
Lewin flew back again to Rio from Manaus with the staff but while the squad will head on to Sao Paulo afterwards this week for Thursdays crunch clash with Uruguay, the Arsenal guy Englands physio due to the fact 1996 - will be traveling house to the Uk.
Lewin stated : " I am absolutely devastated to be heading property. A lot of hard operate, planning and preparing have gone into this tournament.
"England has a excellent backroom employees who will keep on to supply superb support to the players and administration.
" I'd like to thank my England colleagues and the FIFA health-related officers at the Amazonia Arena for their great, skilled therapy.
"And of program, I would like the England group all the greatest for the rest of the tournament."
Hodgson claimed : It is incredibly unfortunate for Gary and us that this accident transpired. We will of program skip him as he's an incredibly skilled and common member of workers.
" Nonetheless, we would like him a speedy restoration and know he'll be cheering us on from back residence."
Lewin is the second England staff members member to endure an injury on this tour.
Assistant coach Ray Lewington necessary surgery on his knee following waking up in agony during the squad's heat -up camp in Miami.
Lewington has remained with the squad, while he has been provided a forged for his remaining leg.